Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration.
Identifieur interne : 001933 ( Main/Exploration ); précédent : 001932; suivant : 001934Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration.
Auteurs : C. Roger [France] ; L. Muller [France] ; S C Wallis [Australie] ; B. Louart [France] ; G. Saissi [France] ; J. Lipman [Australie] ; J Y Lefrant [France] ; J A Roberts [Royaume-Uni]Source :
- The Journal of antimicrobial chemotherapy [ 1460-2091 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacokinetics : Anti-Bacterial Agents, Linezolid.
- Aged, Blood Chemical Analysis, Chromatography, Critical Illness, Female, Hemodiafiltration, Hemofiltration, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Prospective Studies.
Abstract
Few data are available to guide linezolid dosing during renal replacement therapy. The objective of this study was to compare the population pharmacokinetics of linezolid during continuous venovenous haemofiltration (CVVHF, 30 mL/kg/h) and continuous venovenous haemodiafiltration (CVVHDF, 15 mL/kg/h + 15 mL/kg/h).
DOI: 10.1093/jac/dkv349
PubMed: 26538503
Affiliations:
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Roger</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France claire.roger@chu-nimes.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Muller, L" sort="Muller, L" uniqKey="Muller L" first="L" last="Muller">L. 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Roger</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France claire.roger@chu-nimes.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Muller, L" sort="Muller, L" uniqKey="Muller L" first="L" last="Muller">L. Muller</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Wallis, S C" sort="Wallis, S C" uniqKey="Wallis S" first="S C" last="Wallis">S C Wallis</name><affiliation wicri:level="1"><nlm:affiliation>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Louart, B" sort="Louart, B" uniqKey="Louart B" first="B" last="Louart">B. Louart</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Saissi, G" sort="Saissi, G" uniqKey="Saissi G" first="G" last="Saissi">G. Saissi</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Lipman, J" sort="Lipman, J" uniqKey="Lipman J" first="J" last="Lipman">J. Lipman</name><affiliation wicri:level="1"><nlm:affiliation>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Lefrant, J Y" sort="Lefrant, J Y" uniqKey="Lefrant J" first="J Y" last="Lefrant">J Y Lefrant</name><affiliation wicri:level="3"><nlm:affiliation>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service des réanimations, Pôle Anesthésie Réanimation Douleur Urgence, CHU Nîmes, Place du Professeur Robert Debré, 30 029 Nîmes cedex 9, France Equipe d'Accueil 2992, Faculté de Médecine de Nîmes, Université de Montpellier, Chemin du Carreau de Lanes, Nimes</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Nîmes</settlement></placeName></affiliation></author><author><name sortKey="Roberts, J A" sort="Roberts, J A" uniqKey="Roberts J" first="J A" last="Roberts">J A Roberts</name><affiliation wicri:level="1"><nlm:affiliation>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia Pharmacy Department, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia Pharmacy Department, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of antimicrobial chemotherapy</title><idno type="eISSN">1460-2091</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Anti-Bacterial Agents (pharmacokinetics)</term><term>Blood Chemical Analysis</term><term>Chromatography</term><term>Critical Illness</term><term>Female</term><term>Hemodiafiltration</term><term>Hemofiltration</term><term>Humans</term><term>Linezolid (pharmacokinetics)</term><term>Male</term><term>Microbial Sensitivity Tests</term><term>Middle Aged</term><term>Prospective Studies</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Analyse chimique du sang</term><term>Antibactériens (pharmacocinétique)</term><term>Chromatographie</term><term>Femelle</term><term>Humains</term><term>Hémodiafiltration</term><term>Hémofiltration</term><term>Linézolide (pharmacocinétique)</term><term>Maladie grave</term><term>Mâle</term><term>Sujet âgé</term><term>Tests de sensibilité microbienne</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Linezolid</term></keywords><keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Antibactériens</term><term>Linézolide</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Blood Chemical Analysis</term><term>Chromatography</term><term>Critical Illness</term><term>Female</term><term>Hemodiafiltration</term><term>Hemofiltration</term><term>Humans</term><term>Male</term><term>Microbial Sensitivity Tests</term><term>Middle Aged</term><term>Prospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Analyse chimique du sang</term><term>Chromatographie</term><term>Femelle</term><term>Humains</term><term>Hémodiafiltration</term><term>Hémofiltration</term><term>Maladie grave</term><term>Mâle</term><term>Sujet âgé</term><term>Tests de sensibilité microbienne</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Few data are available to guide linezolid dosing during renal replacement therapy. The objective of this study was to compare the population pharmacokinetics of linezolid during continuous venovenous haemofiltration (CVVHF, 30 mL/kg/h) and continuous venovenous haemodiafiltration (CVVHDF, 15 mL/kg/h + 15 mL/kg/h).</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>Royaume-Uni</li></country><region><li>Languedoc-Roussillon</li><li>Occitanie (région administrative)</li></region><settlement><li>Nîmes</li></settlement></list><tree><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Roger, C" sort="Roger, C" uniqKey="Roger C" first="C" last="Roger">C. Roger</name></region><name sortKey="Lefrant, J Y" sort="Lefrant, J Y" uniqKey="Lefrant J" first="J Y" last="Lefrant">J Y Lefrant</name><name sortKey="Louart, B" sort="Louart, B" uniqKey="Louart B" first="B" last="Louart">B. Louart</name><name sortKey="Muller, L" sort="Muller, L" uniqKey="Muller L" first="L" last="Muller">L. Muller</name><name sortKey="Saissi, G" sort="Saissi, G" uniqKey="Saissi G" first="G" last="Saissi">G. Saissi</name></country><country name="Australie"><noRegion><name sortKey="Wallis, S C" sort="Wallis, S C" uniqKey="Wallis S" first="S C" last="Wallis">S C Wallis</name></noRegion><name sortKey="Lipman, J" sort="Lipman, J" uniqKey="Lipman J" first="J" last="Lipman">J. Lipman</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Roberts, J A" sort="Roberts, J A" uniqKey="Roberts J" first="J A" last="Roberts">J A Roberts</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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